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Clinicopathological Characteristics and Prognostic Impact of KRAS Mutations in Non-Small Cell Lung Cancer.

Medicina (Kaunas, Lithuania) - 23 May 2026

Aydın Tayyip İlker, Öztürk Gökhan, Akkuş Aysun Fatma, Taştekin Ebru, Topaloğlu Sernaz, Erdoğan Bülent, Küçükarda Ahmet, Hacıoğlu Muhammet Bekir

Abstract excerpt

Background/Objectives: KRAS mutations are among the most common oncogenic driver alterations in non-small cell lung cancer (NSCLC) and define a biologically heterogeneous disease. In the current era of molecular oncology, with targeted therapies increasingly incorporated into clinical practice, the prognostic relevance of individual KRAS mutation subtypes and their relationship with immune biomarkers such as...

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Identifiers

PMID: 42356023
DOI: 10.3390/medicina62061011
PMCID: PMC13304285

Genes

KRAS

Variants

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