Article
Prognostic value of specific KRAS mutations in lung adenocarcinomas.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 1997
Siegfried J M, Gillespie A T, Mera R, Casey T J, Keohavong P, Testa J R, Hunt J D
Abstract excerpt
Adenocarcinomas of the lung remain a significant public health problem. Locally defined (stage I) tumors are considered amenable to resection with curative intent. However, only about 45% of these patients survive for 5 years. The median survival for more advanced tumors is drastically lower. Much research has been focused on identifying a valid genetic biomarker of prognosis. Mutations of the proto-oncogene KRAS...
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