Article
Prognostic and Predictive Value in KRAS in Non-Small-Cell Lung Cancer: A Review.
JAMA oncology - 1 Jun 2016
Wood Kevin, Hensing Thomas, Malik Raeva, Salgia Ravi
Abstract excerpt
IMPORTANCE: Lung cancer is the leading cause of cancer deaths worldwide, with non-small-cell lung cancer (NSCLC) constituting more than 80% of all lung cancers. Non-small-cell lung cancer is a heterogenous disease, with multiple different oncogenic driver mutations representing possible therapeutic targets. The vi-Ki-ras2 Kirsten rat sarcoma viral oncogene (KRAS) represents one of the most common oncogenic driver...
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