Article
KISS1 gene polymorphisms in Korean girls with central precocious puberty.
Journal of Korean medical science - 1 Aug 2014
Rhie Young-Jun, Lee Kee-Hyoung, Ko Jung Min, Lee Woo Jung, Kim Jung Hyun, Kim Ho-Seong
Abstract excerpt
Kisspeptin/G-protein couple receptor-54 (GPR54) system plays a key role in the activation of the gonadotropic axis at puberty. Central precocious puberty (CPP) is caused by the premature activation of hypothalamic gonadotropin-releasing hormone secretion. This study was aimed to identify KISS1 gene variations and to investigate the associations between KISS1 gene variations and CPP in Korean girls. All coding...
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