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Article

Association of Polymorphisms in the Kisspeptin/GPR54 Pathway Genes With Risk of Early Puberty in Chinese Girls.

The Journal of clinical endocrinology and metabolism - 1 Apr 2020

Li Di, Wu Yu, Cheng Jinquan, Liu Liegang, Li Xiaoheng, Chen Dingyan, Huang Suli, Wen Ying, Ke Yuebin, Yao Yao, Su Zhe, Zhou Li

Abstract excerpt

CONTEXT AND OBJECTIVE: This case control study was designed to investigate the association between mutation of 10 single nucleotide polymorphism (SNP) loci (rs1132506, rs5780218, rs192636495, rs4889, rs184749, rs12985070, , , , and ) in all 5 genes (KISS1, GPR54, PLCB1, PRKCA, and ITPR1) in the kisspeptin/GPR54 pathway and the risk of early puberty in Chinese Han girls. DESIGN...

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PMID: 32160304
DOI: 10.1210/clinem/dgz229

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