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Article

Polymorphism rs5780218, rs12998 and rs10158616 in KISS1 gene among the Hubei province Chinese girls with the central precocious puberty.

Endocrine - 1 Jun 2024

Dong Lijuan, Zhou Weiguang, Lin Zhongchao, Tang Lingyu, Deng Xinyi, Chen Bifeng, Huang Wei, Xiong Qiantao

Abstract excerpt

PURPOSE: Central precocious puberty (CPP) results from early activation of the hypothalamic-pituitary-gonadal (HPG) axis. To elucidate the molecular genetic basis of CPP, we here investigated the effects of polymorphism rs5780218, rs12998 and rs10158616 in KISS1 gene on CPP susceptibility. METHODS: The three KISS1 gene polymorphisms were genotyped by the polymerase chain reaction-restriction fragment length...

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Source

Identifiers

PMID: 38358556
DOI: 10.1007/s12020-024-03716-4

Genes

KISS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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