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Article

MKRN3 and KISS1R mutations in precocious and early puberty.

Italian journal of pediatrics - 30 Mar 2020

Pagani Sara, Calcaterra Valeria, Acquafredda Gloria, Montalbano Chiara, Bozzola Elena, Ferrara Pietro, Gasparri Manuela, Villani Alberto, Bozzola Mauro

Abstract excerpt

BACKGROUND: Pubertal timing is known to be influenced by interactions among various genetic, nutritional, environmental and socio-economic factors, although the ultimate mechanisms underlying the increase in pulsatile GnRH secretion at puberty have yet to be fully elucidated. The aim of our research was to verify the role of KISSR1 (previously named GPR54) and MKRN3 genes on pubertal timing. METHODS: We analyzed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32228714
DOI: 10.1186/s13052-020-0808-6
PMCID: PMC7104496

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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