Article

rs4889 and rs5782018 polymorphisms of KISS1 gene as genetic predisposing factor for PCOS in Indonesian women

2025-09-09

Abstract excerpt

Abstract* Background A disruption in the function of the HPG axis in PCOS causes increased frequency and amplitude of gonadotropin-releasing hormone (GnRH) pulsatility in the hypothalamus. Single nucleotide polymorphisms (SNPs) in the KISS1 gene may contribute to this dysregulation and promote disease development. The present study aims to determine the impact of KISS1 gene polymorphisms and haplotypes on the deve...

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Literature Corpus work: 5bb2bcbd-c5c1-57c9-bc36-d7ad851c33ed
DOI: 10.12688/f1000research.168971.1

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