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Article

Nonparametric method for detecting imprinting effect using all members of general pedigrees with missing data.

Journal of human genetics - 1 Oct 2014

Zhang Fangyuan, Lin Shili

Abstract excerpt

Imprinting effects can lead to parent-of-origin patterns in complex human diseases. For a diallelic marker locus, Pedigree Parental-Asymmetry Test (PPAT) and its extension MCPPAT using pedigrees allowing for missing genotypes are simple and powerful for detecting imprinting effects. However, these approaches only take affected offspring into consideration, thus not making full use of the data available. In this...

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Source

Identifiers

PMID: 25119724
DOI: 10.1038/jhg.2014.67

Genes

PPAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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