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Article

Detection of parent-of-origin effects using general pedigree data.

Genetic epidemiology - 1 Feb 2010

Zhou Ji-Yuan, Ding Jie, Fung Wing K, Lin Shili

Abstract excerpt

Genomic imprinting is an important epigenetic factor in complex traits study, which has generally been examined by testing for parent-of-origin effects of alleles. For a diallelic marker locus, the parental-asymmetry test (PAT) based on case-parents trios and its extensions to incomplete nuclear families (1-PAT and C-PAT) are simple and powerful for detecting parent-of-origin effects. However, these methods are...

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Identifiers

PMID: 19676055
DOI: 10.1002/gepi.20445
PMCID: PMC3011930

Genes

PPAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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