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Article

Evolution and developmental regulation of the major histocompatibility complex.

Critical reviews in immunology - 1 Jan 1995

Salter-Cid L, Flajnik M F

Abstract excerpt

The ontogeny and evolution of the major histocompatibility complex (MHC) are blossoming fields that grant insight into the origins of the adaptive immune system and into the strategies adopted by particular groups of vertebrates for expression of MHC during development. This review surveys general topics concerning MHC evolution, with special emphasis on the significance of linkage of gene families within the...

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PMID: 8519422
DOI: 10.1615/critrevimmunol.v15.i1.20

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