Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicle

doi:10.1186/s12862-023-02107-z

Article

Ancient lineages of the keratin-associated protein (KRTAP) genes and their co-option in the evolution of the hair follicle

20 Mar 2023

Abstract excerpt

BLAST searches against the human genome showed that of the 93 keratin-associated proteins (KRTAPs) of Homo sapiens, 53 can be linked by sequence similarity to an H. sapiens metallothionein and 16 others can be linked similarly to occludin, while the remaining KRTAPs can themselves be linked to one or other of those 69 directly-linked proteins. The metallothionein-linked KRTAPs comprise the high-sulphur and...

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