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Chitinase family GH18: evolutionary insights from the genomic history of a diverse protein family

26 Jun 2007

Abstract excerpt

BACKGROUND: Chitinases (EC.3.2.1.14) hydrolyze the beta-1,4-linkages in chitin, an abundant N-acetyl-beta-D-glucosamine polysaccharide that is a structural component of protective biological matrices such as insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 (GH18) family of chitinases is an ancient gene family widely expressed in archea, prokaryotes and eukaryotes. Mammals are not known to...

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PMID: 17594485
DOI: 10.1186/1471-2148-7-96

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