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Article

The chromosomal duplication model of the major histocompatibility complex

1 Feb 1999

Abstract excerpt

The major histocompatibility complex (MHC) is a genetic region that has been extensively studied by immunologists, molecular biologists, and evolutionary biologists. Nevertheless, our knowledge of how the MHC acquired its present-day organization is quite limited. The recent discovery that the mammalian genome contains regions paralogous to the MHC has led us to the proposal that the MHC region of jawed...

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PMID: 10319248
DOI: 10.1111/j.1600-065x.1999.tb01379.x

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