Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Somatic alterations and dysregulation of epigenetic modifiers in cancers.

Biochemical and biophysical research communications - 5 Dec 2014

Aumann Shlomzion, Abdel-Wahab Omar

Abstract excerpt

Genomic discovery efforts in patients with cancer have been critical in identifying a recurrent theme of mutations in epigenetic modifiers. A number of novel and exciting basic biological findings have come from this work including the discovery of an enzymatic pathway for DNA cytosine demethylation, a link between cancer metabolism and epigenetics, and the critical importance of post-translational modifications...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Methylation
Share to Epigenesis, Genetic
Share to IDH1 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to IDH2 gene

Share to Histones

Share to Mutation

Share to Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25111821
DOI: 10.1016/j.bbrc.2014.08.004
PMCID: PMC6630175

Genes

IDH1
IDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Somatic alterations and dysregulation of epigenetic modifiers in cancers.PMID 25111821Read ↗

Mutations in Epigenetic Modifiers in Myeloid Malignancies and the Prospect of Novel Epigenetic-Targeted TherapySemantic proximity Read ↗

Molecular pathways: protein methyltransferases in cancer.Semantic proximity Read ↗

Epigenetic alterations in hematopoietic malignancies.Semantic proximity Read ↗

Mutations in epigenetic modifiers in the pathogenesis and therapy of acute myeloid leukemia.Semantic proximity Read ↗

The role of mutations in epigenetic regulators in myeloid malignancies.Semantic proximity Read ↗

Epigenetic changes in cancer.Semantic proximity Read ↗

Epigenetic deregulation in myeloid malignanciesSemantic proximity Read ↗

DNA Methylation Malleability and Dysregulation in Cancer Progression: Understanding the Role of PARP1Semantic proximity Read ↗

Cytosine modifications in myeloid malignancies.Semantic proximity Read ↗

Mutations in epigenetic modifiers in acute myeloid leukemia and their clinical utility.Semantic proximity Read ↗

Epigenetics and OncologySemantic proximity Read ↗

Epigenetic changes in solid and hematopoietic tumors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.