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Article

Epigenetic alterations in hematopoietic malignancies.

International journal of hematology - 1 Oct 2012

Chung Young Rock, Schatoff Emma, Abdel-Wahab Omar

Abstract excerpt

Gene discovery efforts in patients with hematopoietic malignancies have brought to the forefront a series of mutations in genes thought to be involved in the epigenetic regulation of gene transcription. These mutations occur in genes known, or suspected, to play a role in modifying cytosine nucleotides on DNA and/or altering the state of histone modifications. Genes such as ASXL1, DNMT3A, EZH2, IDH1/2, MLL1, and...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

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Share to Protein Processing, Post-Translational

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Source

Identifiers

PMID: 23015417
DOI: 10.1007/s12185-012-1181-z

Genes

IDH1
TET2
ASXL1
CREBBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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