Article
Toll-like receptor 7 variations are associated with the susceptibility to HCV infection among Chinese females.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Oct 2014
Yue Ming, Gao Chun-fang, Wang Jia-jia, Wang Chang-jun, Feng Le, Wang Jie, Yu Rong-bin, Peng Zhi-hang, Xue Xing-xin, Cai Li, Fan Nai-jun, Zhang Yun, Deng Xiao-zhao
Abstract excerpt
Toll-like receptors 7 (TLR7) play a crucial role in provoking an immune response in HCV infection. We aimed to investigate whether single nucleotide polymorphisms (SNPs) of TLR7, including rs179009, rs179010 and rs179012, affect the outcomes of HCV infection among the Chinese population. A total of 1767 Chinese Han individuals were enrolled. The distribution of SNP frequencies among three groups with different...
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