Article
Toll like receptor7 polymorphisms in relation to disease susceptibility and progression in Chinese patients with chronic HBV infection.
Scientific reports - 29 Sept 2017
Zhu Junping, Zhang Tong, Cao Lina, Li Aixin, Zheng Kai, Zhang Nan, Su Bin, Chen Zhiyun, Chen Ning, Wu Hao, He Qiushui
Abstract excerpt
Toll-like receptors (TLRs) play a key role in innate and adaptive immunity, protecting the host from viral pathogens. We studied the effect of TLR7 polymorphisms on disease susceptibility and progression of chronic hepatitis B (CHB) infection in Chinese adults. Blood samples were taken from 612 patients with confirmed CHB, hepatitis B virus (HBV)-related liver cirrhosis (LC) or hepatocellular carcinoma (HCC) and...
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