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Article

Sex-specific association between X-linked Toll-like receptor 7 with the outcomes of hepatitis C virus infection.

Gene - 15 Sept 2014

Yue Ming, Feng Le, Tang Shai-di, Wang Jia-jia, Xue Xing-xin, Ding Wei-liang, Zhang Yun, Deng Xiao-zhao

Abstract excerpt

Toll-like receptor 7 (TLR7) senses hepatitis C virus (HCV) infection and drives the host specific innate and adaptive immune response. The aim of this study was to estimate the distributions of TLR7 single nucleotide polymorphisms (SNPs), including rs179019 and rs3853839, as well as the effect of TLR7 gene variants on TLR7 mRNA expression and cytokine production in response to TLR7 agonist in vitro. TLR7 SNP...

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Source

Identifiers

PMID: 25034660
DOI: 10.1016/j.gene.2014.07.040

Genes

TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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