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Article

TLR7 and TLR8 gene variations and susceptibility to hepatitis C virus infection.

PloS one - 1 Jan 2011

Wang Chiou-Huey, Eng Hock-Liew, Lin Kuei-Hsiang, Chang Cheng-Hsien, Hsieh Chi-An, Lin Yen-Li, Lin Tsun-Mei

Abstract excerpt

Toll-like receptors (TLRs) play pivotal roles in the innate immune system and control inflammatory responses and adaptive immunity. We previously evaluated associations between TLR7 and TLR8 gene SNPs and susceptibility to hepatitis C virus (HCV) infection. Our results suggested that TLR7IVS2-151G and TLR8-129G alleles were present at higher frequency in males of an HCV-infected group as compared to a control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22022576
DOI: 10.1371/journal.pone.0026235
PMCID: PMC3192790

Genes

TLR8
TLR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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