Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variations in toll-like receptors 7 and 8 modulate natural hepatitis C outcomes and liver disease progression.

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2018

Fakhir Fatima-Zohra, Lkhider Mustapha, Badre Wafaa, Alaoui Rhimou, Meurs Eliane F, Pineau Pascal, Ezzikouri Sayeh, Benjelloun Soumaya

Abstract excerpt

BACKGROUND & AIMS: The natural outcomes of hepatitis C virus (HCV) as well as the progression of the liver disease are highly variable and depend primarily on an efficient immune response. As toll-like receptors seven (TLR7) and eight (TLR8) are important effectors of the innate immunity, this study aims to evaluate the association between TLR7 and TLR8 polymorphisms and the HCV infection outcomes in Moroccan...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Disease Progression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis C

Share to Logistic Models

Share to Sex Factors

Share to Toll-Like Receptor 7

Share to Toll-Like Receptor 8

Source

Identifiers

PMID: 28752959
DOI: 10.1111/liv.13533

Genes

TLR7
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variations in toll-like receptors 7 and 8 modulate natural hepatitis C outcomes and liver disease progression.PMID 28752959Read ↗

Sex-specific association between X-linked Toll-like receptor 7 with the outcomes of hepatitis C virus infection.Semantic proximity Read ↗

The association of single nucleotide polymorphisms of Toll-like receptor 3, Toll-like receptor 7 and Toll-like receptor 8 genes with the susceptibility to HCV infection.Semantic proximity Read ↗

Single nucleotide polymorphisms of toll-like receptor 7 in hepatitis C virus infection patients from a high-risk chinese population.Semantic proximity Read ↗

Toll-like receptor 7 variations are associated with the susceptibility to HCV infection among Chinese females.Semantic proximity Read ↗

Single nucleotide polymorphisms of toll-like receptor 7 and toll-like receptor 9 in hepatitis C virus infection patients from central China.Semantic proximity Read ↗

TLR7 and TLR8 gene variations and susceptibility to hepatitis C virus infection.Semantic proximity Read ↗

A Toll-like receptor 7 single nucleotide polymorphism protects from advanced inflammation and fibrosis in male patients with chronic HCV-infection.Semantic proximity Read ↗

Association of TLR7 single nucleotide polymorphisms with chronic HCV-infection and response to interferon-a-based therapy.Semantic proximity Read ↗

Toll like receptor7 polymorphisms in relation to disease susceptibility and progression in Chinese patients with chronic HBV infection.Semantic proximity Read ↗

Genetic variation in the interleukin-28B gene is associated with spontaneous clearance and progression of hepatitis C virus in Moroccan patients.Semantic proximity Read ↗

Immunogenetic studies of the hepatitis C virus infection in an era of pan-genotype antiviral therapies - Effective treatment is coming.Semantic proximity Read ↗

Association between Toll-Like Receptor 3 (TLR3) rs3775290, TLR7 rs179008, TLR9 rs352140 and Chronic HCVSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.