Effects of TLR7 Polymorphisms on the Susceptibility and Progression of HIV-1 Infection in Chinese MSM Population.

doi:10.3389/fimmu.2020.589010

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Effects of TLR7 Polymorphisms on the Susceptibility and Progression of HIV-1 Infection in Chinese MSM Population.

Frontiers in immunology - 1 Jan 2020

Zhang Tong, Zhu Junping, Su Bin, Cao Lina, Li Zhen, Wei Huanhuan, Huang Xiaojie, Zheng Kai, Li Aixin, Chen Ning, Liu Lifeng, Xia Wei, Wu Hao, He Qiushui

Abstract excerpt

Toll-like receptor (TLR) 7 plays a key role in innate and adaptive immunity for HIV-1 infection. We evaluated the effect of TLR7 polymorphisms on disease susceptibility and progression of HIV-1 infection in Chinese MSM (men who have sex with men). Blood samples were taken from 270 patients with laboratory confirmed HIV infection, 196 male controls were tested, and three TLR7 intronic polymorphisms (rs179010-C >...

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Identifiers

PMID: 33193416
DOI: 10.3389/fimmu.2020.589010
PMCID: PMC7649213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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