Article
Analysis of circulating tumor DNA to monitor metastatic breast cancer.
The New England journal of medicine - 28 Mar 2013
Dawson Sarah-Jane, Tsui Dana W Y, Murtaza Muhammed, Biggs Heather, Rueda Oscar M, Chin Suet-Feung, Dunning Mark J, Gale Davina, Forshew Tim, Mahler-Araujo Betania, Rajan Sabrina, Humphray Sean, Becq Jennifer, Halsall David, Wallis Matthew, Bentley David, Caldas Carlos, Rosenfeld Nitzan
Abstract excerpt
BACKGROUND: The management of metastatic breast cancer requires monitoring of the tumor burden to determine the response to treatment, and improved biomarkers are needed. Biomarkers such as cancer antigen 15-3 (CA 15-3) and circulating tumor cells have been widely studied. However, circulating ce...
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