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Article

Brain-derived neurotrophic factor (BDNF)-epigenetic regulation in unipolar and bipolar affective disorder.

Journal of affective disorders - 1 Oct 2014

Carlberg Laura, Scheibelreiter Janine, Hassler Melanie R, Schloegelhofer Monika, Schmoeger Michaela, Ludwig Birgit, Kasper Siegfried, Aschauer Harald, Egger Gerda, Schosser Alexandra

Abstract excerpt

BACKGROUND: Alterations of brain-derived neurotrophic factor (BDNF) DNA methylation at specific BDNF promoters and corresponding gene expressions are associated with pathology and the response to antidepressant (AD) therapy in affective disorders such as major depressive disorder (MDD) and bipolar disorder (BD). METHODS: Genomic DNA was derived from peripheral blood mononuclear cells (PBMCs) and was bisulfite...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25106037
DOI: 10.1016/j.jad.2014.07.022

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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