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Article

Epigenetic mechanisms underlying the role of brain-derived neurotrophic factor in depression and response to antidepressants.

The Journal of experimental biology - 1 Jan 2015

Duclot Florian, Kabbaj Mohamed

Abstract excerpt

Major depressive disorder (MDD) is a devastating neuropsychiatric disorder encompassing a wide range of cognitive and emotional dysfunctions. The prevalence of MDD is expected to continue its growth to become the second leading cause of disease burden (after HIV) by 2030. Despite an extensive research effort, the exact etiology of MDD remains elusive and the diagnostics uncertain. Moreover, a marked...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25568448
DOI: 10.1242/jeb.107086
PMCID: PMC4286703

Genes

BDNF

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