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Evaluation of DNA methylation in BDNF , SLC6A4 , NR3C1 and FKBP5 before and after treatment with selective serotonin-reuptake inhibitor in major depressive disorder

1 Oct 2022

Abstract excerpt

Aim: To identify the DNA methylation status of related genes in major depressive disorder following selective serotonin-reuptake inhibitor treatment. Materials & methods: 45 patients with major depressive disorder and 45 healthy volunteers were considered experimental and control groups, respectively. High-resolution melting real-time PCR was implemented to evaluate DNA methylation. Results: After 100 days of...

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PMID: 36377555
DOI: 10.2217/epi-2022-0246

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