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Article

BDNF promoter methylation and genetic variation in late-life depression.

Translational psychiatry - 18 Aug 2015

Januar V, Ancelin M-L, Ritchie K, Saffery R, Ryan J

Abstract excerpt

The regulation of the brain-derived neurotrophic factor (BDNF) is important for depression pathophysiology and epigenetic regulation of the BDNF gene may be involved. This study investigated whether BDNF methylation is a marker of depression. One thousand and twenty-four participants were recruited as part of a longitudinal study of psychiatric disorders in general population elderly (age ⩾ 65). Clinical levels...

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Identifiers

PMID: 26285129
DOI: 10.1038/tp.2015.114
PMCID: PMC4564567

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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