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Article

Selective DNA methylation of BDNF promoter in bipolar disorder: differences among patients with BDI and BDII.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2012

D'Addario Claudio, Dell'Osso Bernardo, Palazzo Maria Carlotta, Benatti Beatrice, Lietti Licia, Cattaneo Elisabetta, Galimberti Daniela, Fenoglio Chiara, Cortini Francesca, Scarpini Elio, Arosio Beatrice, Di Francesco Andrea, Di Benedetto Manuela, Romualdi Patrizia, Candeletti Sanzio, Mari Daniela, Bergamaschini Luigi, Bresolin Nereo, Maccarrone Mauro, Altamura A Carlo

Abstract excerpt

The etiology of bipolar disorder (BD) is still poorly understood, involving genetic and epigenetic mechanisms as well as environmental contributions. This study aimed to investigate the degree of DNA methylation at the promoter region of the brain-derived neurotrophic factor (BDNF) gene, as one o...

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Identifiers

PMID: 22353757
DOI: 10.1038/npp.2012.10
PMCID: PMC3358733

Genes

BDNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22353757-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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