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Article

The CCR5Δ32 allele is not a major predisposing factor for severe H1N1pdm09 infection.

BMC research notes - 7 Aug 2014

Sironi Manuela, Cagliani Rachele, Pontremoli Chiara, Rossi Marianna, Migliorino Guglielmo, Clerici Mario, Gori Andrea

Abstract excerpt

BACKGROUND: Host genetic factors are thought to modulated the severity of disease caused by infection with the 2009 H1N1 pandemic influenza virus (H1N1pdm09). The human CCR5 gene encodes a cytokine receptor important for cell-mediated immune response against H1N1pdm09. A 32-bp polymorphic deletion in the coding sequence of CCR5, the so-called CCR5Δ32 allele, segregates in populations of European ancestry with a...

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Source

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Identifiers

PMID: 25100510
DOI: 10.1186/1756-0500-7-504
PMCID: PMC4132245

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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