Article
IFITM3 and severe influenza virus infection. No evidence of genetic association.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology - 1 Nov 2016
López-Rodríguez M, Herrera-Ramos E, Solé-Violán J, Ruíz-Hernández J J, Borderías L, Horcajada J P, Lerma-Chippirraz E, Rajas O, Briones M, Pérez-González M C, García-Bello M A, López-Granados E, Rodriguez de Castro F, Rodríguez-Gallego C
Abstract excerpt
Influenza virus infection (IVI) is typically subclinical or causes a self-limiting upper respiratory disease. However, in a small subset of patients IVI rapidly progresses to primary viral pneumonia (PVP) with respiratory failure; a minority of patients require intensive care unit admission. Inherited and acquired variability in host immune responses may influence susceptibility and outcome of IVI. However, the...
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