Article
The His131Arg substitution in the FCGR2A gene (rs1801274) is not associated with the severity of influenza A(H1N1)pdm09 infection.
BMC research notes - 7 Jun 2016
Maestri Alvino, Sortica Vinicius Albuquerque, Ferreira Deimy Lima, de Almeida Ferreira Jessylene, Amador Marcos Antônio Trindade, de Mello Wyller Alencar, Santos Sidney Emanuel Batista, Sousa Rita Catarina Medeiros
Abstract excerpt
BACKGROUND: The virulence and pathogenicity of different influenza strains are responsible for a more or less severe disease. Recent studies have attempted to understand how host genetic factors may influence the clinical presentation of the disease. In the present study, the His131Arg (rs1801274) polymorphism was investigated in individuals from a Brazilian admixed population with a diagnosis of influenza...
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