Article
Cancer phenotype as the outcome of an evolutionary game between normal and malignant cells.
British journal of cancer - 6 Oct 2009
Dingli D, Chalub F A C C, Santos F C, Van Segbroeck S, Pacheco J M
Abstract excerpt
BACKGROUND: There is variability in the cancer phenotype across individuals: two patients with the same tumour may experience different disease life histories, resulting from genetic variation within the tumour and from the interaction between tumour and host. Until now, phenotypic variability has precluded a clear-cut identification of the fundamental characteristics of a given tumour type. METHODS: Using...
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