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Article

Cell Fitness: More Than Push-Ups.

International journal of molecular sciences - 7 Jan 2021

Ferrari Adam James, Drapkin Ronny, Gogna Rajan

Abstract excerpt

Cell competition (CC) is a feature that allows tumor cells to outcompete and eliminate adjacent cells that are deemed less fit. Studies of CC, first described in Drosophila melanogaster, reveal a diversity of underlying mechanisms. In this review, we will discuss three recent studies that expand our understanding of the molecular features governing CC. In particular, we will focus on a molecular fitness...

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PMID: 33430180
DOI: 10.3390/ijms22020518
PMCID: PMC7825606

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