Article
Persistent competition among stem cells and their daughters in the Drosophila ovary germline niche.
Development (Cambridge, England) - 1 Mar 2009
Rhiner Christa, Díaz Begoña, Portela Marta, Poyatos Juan F, Fernández-Ruiz Irene, López-Gay Jesús M, Gerlitz Offer, Moreno Eduardo
Abstract excerpt
Cell competition is a short-range cell-cell interaction leading to the proliferation of winner cells at the expense of losers, although either cell type shows normal growth in homotypic environments. Drosophila Myc (dMyc; Dm-FlyBase) is a potent inducer of cell competition in wing epithelia, but its role in the ovary germline stem cell niche is unknown. Here, we show that germline stem cells (GSCs) with relative...
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