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Article

Stem cell competition in the gut: insights from multi-scale computational modelling.

Journal of the Royal Society, Interface - 1 Aug 2016

Thalheim Torsten, Buske Peter, Przybilla Jens, Rother Karen, Loeffler Markus, Galle Joerg

Abstract excerpt

Three-dimensional (3D) computational tissue models can provide a comprehensive description of tissue dynamics at the molecular, cellular and tissue level. Moreover, they can support the development of hypotheses about cellular interactions and about synergies between major signalling pathways. We exemplify these capabilities by simulation of a 3D single-cell-based model of mouse small intestinal crypts. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27534699
DOI: 10.1098/rsif.2016.0218
PMCID: PMC5014057

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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