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Polymorphisms in the DC-SIGN gene and their association with the severity of hand, foot, and mouth disease caused by enterovirus 71.

Archives of virology - 1 Apr 2021

Li Ya-Ping, Wang Mu-Qi, Liu Chen-Rui, Deng Hui-Ling, Wu Yuan, Dang Shuang-Suo, Xu Li-Hong

Abstract excerpt

Severe hand, foot, and mouth disease (HFMD) caused by enterovirus 71 (EV71) infection is associated with high mortality and disability. DC-SIGN, a receptor for EV71, is widely distributed in dendritic cells and may influence the severity of HFMD caused by EV71 infection. This observational study attempts to explore whether single-nucleotide polymorphisms (SNPs) in DC-SIGN are related to the severity of...

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PMID: 33590343
DOI: 10.1007/s00705-021-04991-6

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