Article
Analysis of DC-SIGN (CD209) functional variants in patients with tuberculosis.
Human immunology - 1 Oct 2006
Gómez Luis M, Anaya Juan-Manuel, Sierra-Filardi Elena, Cadena Jose, Corbí Angel, Martín Javier
Abstract excerpt
Several lines of evidence suggest that host genetic factors controlling the immune response influence infection by Mycobacterium tuberculosis. Recently, DC-SIGN has been shown to be the major M. tuberculosis receptor on dendritic cells (DCs). The aim of this study was to investigate the influence of DC-SIGN functional polymorphisms -336G/A SNP in the promoter region and insertion/deletion in the "neck" region on...
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