Article
Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients.
Human immunology - 1 Nov 2007
Ben-Ali Meriem, Barreiro Luis B, Chabbou Abdellatif, Haltiti Raja, Braham Ezzeddine, Neyrolles Olivier, Dellagi Koussay, Gicquel Brigitte, Quintana-Murci Lluis, Barbouche Mohamed-Ridha
Abstract excerpt
The C-type lectin DC-SIGN (CD209) is an important pathogen recognition receptor of the innate immune system. Recent studies showed that DC-SIGN is the major receptor of Mycobacterium tuberculosis on human dendritic cells and that polymorphisms in the DC-SIGN promoter region are associated with susceptibility to tuberculosis. In this light, we aimed to study the potential implication of DC-SIGN genetic variation...
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