Article
The Disrupted-in-Schizophrenia-1 Ser704Cys polymorphism and brain neurodevelopmental markers in schizophrenia and healthy subjects.
Progress in neuro-psychopharmacology & biological psychiatry - 2 Jan 2015
Takahashi Tsutomu, Nakamura Mihoko, Nakamura Yukako, Aleksic Branko, Kido Mikio, Sasabayashi Daiki, Takayanagi Yoichiro, Furuichi Atsushi, Nishikawa Yumiko, Noguchi Kyo, Ozaki Norio, Suzuki Michio
Abstract excerpt
Increasing evidence has implicated the role of Disrupted-in-Schizophrenia-1 (DISC1), a potential susceptibility gene for schizophrenia, in early neurodevelopmental processes. However, the effect of its genotype variation on brain morphologic changes related to neurodevelopmental abnormalities in schizophrenia remains largely unknown. This magnetic resonance imaging study examined the association between DISC1...
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