Article
Searching for the major histocompatibility complex psoriasis susceptibility gene.
The Journal of investigative dermatology - 1 May 2002
Capon Francesca, Munro Margo, Barker Jonathan, Trembath Richard
Abstract excerpt
Psoriasis, a common skin disorder, is widely regarded to be multifactorial in origin including gene-gene and gene-environment interactions. Genetic and allelic heterogeneity, multifactorial inheritance, and low penetrance of susceptibility alleles substantially complicate both study design and interpretation of results. Notwithstanding these difficulties, genome-wide scans for psoriasis susceptibility have...
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