Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple Loci within the Major Histocompatibility Complex Confer Risk of Psoriasis

13 Aug 2009

Abstract excerpt

Psoriasis is a common inflammatory skin disease characterized by thickened scaly red plaques. Previously we have performed a genome-wide association study (GWAS) on psoriasis with 1,359 cases and 1,400 controls, which were genotyped for 447,249 SNPs. The most significant finding was for SNP rs12191877, which is in tight linkage disequilibrium with HLA-Cw*0602, the consensus risk allele for psoriasis. However, it...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asthma and respiratory diseases
Share to Psoriasis: Treatment and Pathogenesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to T-cell and B-cell Immunology

Source

Identifiers

PMID: 19680446
DOI: 10.1371/journal.pgen.1000606

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple Loci within the Major Histocompatibility Complex Confer Risk of PsoriasisPMID 19680446Read ↗

Fine mapping major histocompatibility complex associations in psoriasis and its clinical subtypes.Semantic proximity Read ↗

Conditional analysis identifies three novel major histocompatibility complex loci associated with psoriasis.Semantic proximity Read ↗

Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese.Semantic proximity Read ↗

An update on the genetics of psoriasis.Semantic proximity Read ↗

Genomic DNA methylation in HLA-Cw*0602 carriers and non-carriers of psoriasis.Semantic proximity Read ↗

A genetic risk score combining ten psoriasis risk loci improves disease prediction.Semantic proximity Read ↗

Molecular dissection of psoriasis: integrating genetics and biology.Semantic proximity Read ↗

Association of the novel susceptible locus rs9266150 with clinical features of psoriasis vulgaris in the Chinese Han population.Semantic proximity Read ↗

The genetics of psoriasis 2001: the odyssey continues.Semantic proximity Read ↗

Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility.Semantic proximity Read ↗

What have we learned about genetic susceptibility in psoriasis and psoriatic arthritis?Semantic proximity Read ↗

Characterization of the major susceptibility region for psoriasis at chromosome 6p21.3.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.