Article
Aldehyde dehydrogenase 2-a potential genetic risk factor for lung function among southern Chinese: evidence from the Guangzhou Biobank Cohort Study.
Annals of epidemiology - 1 Aug 2014
Au Yeung Shiu Lun, Jiang Chaoqiang, Cheng Kar Keung, Adab Peymane, Lam Kin Bong, Liu Bin, Zhang Weisen, Lam Tai Hing, Leung Gabriel Matthew, Schooling Catherine Mary
Abstract excerpt
PURPOSE: In Asia, moderate alcohol users have better lung function. Never users have more inactive aldehyde dehydrogenase 2 (ALDH2) alleles (A) potentially generating confounding because inactive alleles may increase acetaldehyde exposure and reduce lung function. METHODS: We examined the association of ALDH2 genotypes with percentage predicted lung function (forced expiratory volume in 1 second; forced vital...
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