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Article

Impact of smoking on lung cancer risk is stronger in those with the homozygous aldehyde dehydrogenase 2 null allele in a Japanese population.

Carcinogenesis - 1 Apr 2010

Park Ji Young, Matsuo Keitaro, Suzuki Takeshi, Ito Hidemi, Hosono Satoyo, Kawase Takakazu, Watanabe Miki, Oze Isao, Hida Toyoaki, Yatabe Yasushi, Mitsudomi Tetsuya, Takezaki Toshiro, Tajima Kazuo, Tanaka Hideo

Abstract excerpt

The main lifestyle contributor to acetaldehyde exposure is the drinking of alcoholic beverages, but tobacco smoke also makes some contribution. Although acetaldehyde is associated with upper aerodigestive tract cancer risk, in accordance with genetically determined acetaldehyde metabolism, it is...

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Source

Identifiers

PMID: 20093384
DOI: 10.1093/carcin/bgq021

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20093384-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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