Article
Advances in Factors Affecting ALDH2 Activity and its Mechanisms.
Cardiovascular toxicology - 1 Dec 2024
Liu Yun, Liu Xuemei, Pan Chang
Abstract excerpt
Aldehyde dehydrogenase 2 (ALDH2) is a mitochondrial enzyme primarily involved in the detoxification of alcohol-derived aldehyde and endogenous toxic aldehydes. It exhibits widespread expression across various organs and exerts a broad and significant impact on diverse acute cardiovascular diseases, including acute coronary syndrome, acute aortic dissection, hypoxic pulmonary hypertension, and heart failure. The...
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