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Article

Identification of ALK gene alterations in urothelial carcinoma.

PloS one - 1 Jan 2014

Bellmunt Joaquim, Selvarajah Shamini, Rodig Scott, Salido Marta, de Muga Silvia, Costa Irmgard, Bellosillo Beatriz, Werner Lillian, Mullane Stephanie, Fay André P, O'Brien Robert, Barretina Jordi, Minoche André E, Signoretti Sabina, Montagut Clara, Himmelbauer Heinz, Berman David M, Kantoff Philip, Choueiri Toni K, Rosenberg Jonathan E

Abstract excerpt

BACKGROUND: Anaplastic lymphoma kinase (ALK) genomic alterations have emerged as a potent predictor of benefit from treatment with ALK inhibitors in several cancers. Currently, there is no information about ALK gene alterations in urothelial carcinoma (UC) and its correlation with clinical or pathologic features and outcome. METHODS: Samples from patients with advanced UC and correlative clinical data were...

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Source

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Identifiers

PMID: 25083769
DOI: 10.1371/journal.pone.0103325
PMCID: PMC4118868

Genes

ALK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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