Article
Activation of extracellular regulated kinases (ERK1/2) predicts poor prognosis in urothelial bladder carcinoma and is not associated with B-Raf gene mutations.
Pathology - 1 Jan 2009
Karlou Maria, Saetta Angelica A, Korkolopoulou Penelope, Levidou Georgia, Papanastasiou Pollyanthi, Boltetsou Evmorfia, Isaiadis Dimitrios, Pavlopoulos Petros, Thymara Irene, Thomas-Tsagli Euphemia, Patsouris Efstratios
Abstract excerpt
AIM: The analysis of the presence of B-Raf gene mutations in relation to ERK1/2 activation in bladder urothelial carcinoma (UC), in order to determine their potential role in tumour aggressiveness and patients' survival. METHODS: Polymerase chain reaction-single strand confirmation polymorphism (...
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