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Article

Molecular Characterization of Urothelial Carcinoma of the Bladder and Upper Urinary Tract

21 Nov 2017

Abstract excerpt

PURPOSE: A better understanding of the molecular basis of urothelial carcinoma (UC) is needed to refine the clinical decision-making process. METHODS AND MATERIALS: We performed next-generation sequencing to investigate the mutational and transcriptional profiles of commonly mutated genes in UC using Ampliseq v2. Copy number variations (CNVs) were detected with nCounter assay. Genetic alterations between upper...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 29161613
DOI: 10.1016/j.tranon.2017.10.008

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