Article
Target genes of recurrent chromosomal amplification and deletion in urothelial carcinoma.
Cancer genomics & proteomics - 1 Jan 2000
Weilandt Merlin, Koch Annemarie, Rieder Harald, Deenen René, Schwender Holger, Niegisch Günter, Schulz Wolfgang A
Abstract excerpt
BACKGROUND: Urothelial carcinoma (UC) is characterized by multiple recurrent chromosomal changes on a background of increasing genomic instability. To define target genes of recurrent deletions and amplifications, we explored which gene alterations are common in UC, in two recently established cell lines, BC44 and BC61. MATERIALS AND METHODS: Genes located in regions of gain or deletion in the cell lines were...
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