Article
EGFR alterations and EML4-ALK rearrangement in primary adenocarcinoma of the urinary bladder.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2014
Alexander Riley E, Montironi Rodolfo, Lopez-Beltran Antonio, Williamson Sean R, Wang Mingsheng, Post Kristin M, Sen Joyashree D, Arnold Ashley K, Zhang Shaobo, Wang Xiaoyan, Koch Michael O, Hahn Noah M, Masterson Timothy A, MacLennan Gregory T, Davidson Darrell D, Compérat Eva, Cheng Liang
Abstract excerpt
The identification of mutations in epidermal growth factor receptor (EGFR) and translocations involving anaplastic lymphoma kinase (ALK) in lung adenocarcinoma has drastically changed understanding of the disease and led to the development of targeted therapies. Adenocarcinoma of the urinary bladder is rare and poorly understood at the molecular level. We undertook this study to determine whether EGFR mutations,...
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