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Article

Histopathologic findings associated with APOL1 risk variants in chronic kidney disease.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jan 2015

Larsen Christopher P, Beggs Marjorie L, Saeed Mohammad, Ambruzs Josephine M, Cossey L Nicholas, Messias Nidia C, Walker Patrick D, Freedman Barry I

Abstract excerpt

The effects of nephropathy risk variants in the apolipoprotein L1 gene (APOL1) on renal histopathology in African Americans with arterionephrosclerosis or putative 'hypertension-associated' nephropathy are unknown. APOL1 genotype-phenotype correlations were performed in a blinded manner from renal biopsies in 196 self-reported African Americans with arterionephrosclerosis on kidney biopsy at a large national...

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Share to Apolipoprotein L1
Share to Apolipoproteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Black or African American

Share to Genetic Predisposition to Disease

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Share to Lipoproteins, HDL

Share to Polymorphism, Single Nucleotide

Share to Renal Insufficiency, Chronic

Source

Open in PubMed Open full text

Identifiers

PMID: 25081748
DOI: 10.1038/modpathol.2014.92
PMCID: PMC11163378

Genes

APOL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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